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Swiss Chicken Casserole

This Swiss Chicken Casserole is creamy, cheesy, and baked to golden bubbly perfection. Juicy chicken breasts layered with Swiss cheese and a velvety cream sauce, topped with buttery stuffing—your new comfort food favorite!

  • Total Time: 50 minutes
  • Yield: 4 servings 1x

Ingredients

Scale
  • 4 boneless, skinless chicken breasts
  • 46 slices of Swiss cheese
  • 1 can (10.5 oz) cream of chicken soup
  • 1/2 cup sour cream
  • 1/2 teaspoon garlic powder
  • 1/2 teaspoon onion powder
  • Salt and pepper, to taste
  • 2 cups dry stuffing mix (or seasoned breadcrumbs)
  • 1/4 cup butter, melted
  • Optional garnish: chopped parsley or fresh thyme

Instructions

  1. Preheat oven to 375°F (190°C). Grease a 9×13 baking dish.
  2. Arrange chicken breasts in a single layer in the dish. Season with salt, pepper, garlic powder, and onion powder.
  3. Place 1–2 slices of Swiss cheese on top of each chicken breast.
  4. In a bowl, mix the cream of chicken soup and sour cream until smooth. Pour evenly over the chicken.
  5. Sprinkle the dry stuffing mix over the top of the casserole. Drizzle melted butter evenly over the stuffing.
  6. Bake uncovered for 35–40 minutes, or until the chicken is cooked through and the top is golden and crispy (internal temp should be 165°F).
  7. Let rest for 5 minutes, garnish if desired, and serve warm.

Notes

  • Try different cheeses like provolone, mozzarella, or gouda.
  • Add veggies like sautéed mushrooms, broccoli, or spinach.
  • Use rotisserie chicken for quicker prep.
  • For gluten-free, use gluten-free stuffing or rice crackers.
  • Add a little Dijon mustard for a tangy twist.
  • Author: Selena Trump
  • Prep Time: 10 minutes
  • Cook Time: 40 minutes
  • Category: Dinner
  • Method: Baking
  • Cuisine: American

Nutrition

  • Serving Size: 1 portion
  • Calories: 480
  • Sugar: 2g
  • Sodium: 850mg
  • Fat: 28g
  • Saturated Fat: 14g
  • Unsaturated Fat: 12g
  • Trans Fat: 0g
  • Carbohydrates: 24g
  • Fiber: 1g
  • Protein: 38g
  • Cholesterol: 115mg

Keywords: chicken casserole, swiss chicken, comfort food, easy dinner